To increase a campaigns performance you can create a segment of 'Clickers' to target in DFP.
To begin, you'll need to create a new segment in the Permutive dashboard. Call the new segment something appropriate (e.g. ' Clickers'). In the Behaviour section set 'SlotClicked was performed'. You can set a frequency/recency if required (eg. 'at least 1 time during the last 30 days').
Save the segment, send as a reaction into DFP and use it during campaigns to optimise their performance.